Research paper

Biosensing-by-Learning Direct Targeting Strategy for Enhanced Tumor Sensitization

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Title
Biosensing-by-Learning Direct Targeting Strategy for Enhanced Tumor Sensitization
Content partner
University of Waikato
Collection
ResearchCommons@Waikato
Description

We propose a novel iterative-optimization-inspired direct targeting strategy (DTS) for smart nanosystems, which harness swarms of externally manipulable nanoswimmers assembled by magnetic nanoparticles (MNPs) for knowledge-aided tumor sensitization and targeting. We aim to demonstrate through computational experiments that the proposed DTS can significantly enhance the accumulation of MNPs in the tumor site, which serve as a contrast agent in various medical imaging modalities, by using the s...

Format
Research paper
Research format
Journal article
Date created
2019
Creator
Chen, Yifan / Ali, Muhammad / Shi, Shaolong / Cheang, U. Kei
URL
https://hdl.handle.net/10289/13035
Related subjects
Science & Technology / Life Sciences & Biomedicine / Biochemical Research Methods / Nanoscience & Nanotechnology / Biochemistry & Molecular Biology / Science & Technology - Other Topics / Direct targeting strategy / biosensing-by-learning / tumor-triggered biological gradients / externally manipulable smart nanosystems / magnetic nanoswimmers / iterative optimization / natural computing / contrast-enhanced medical imaging / DRUG-DELIVERY / BLOOD-FLOW / DIELECTRIC-PROPERTIES / IN-VIVO / NANOPARTICLES / MICROENVIRONMENT / AMPLIFICATION / ANGIOGENESIS / SCALE

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