Congestive Heart Failure Leads to Prolongation of the PR Interval and Atrioventricular Junction Enlargement and Ion Channel Remodelling in the Rabbit.

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Title

Congestive Heart Failure Leads to Prolongation of the PR Interval and Atrioventricular Junction Enlargement and Ion Channel Remodelling in the Rabbit.

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Description

Heart failure is a major killer worldwide. Atrioventricular conduction block is common in heart failure; it is associated with worse outcomes and can lead to syncope and bradycardic death. We examine the effect of heart failure on anatomical and ion channel remodelling in the rabbit atrioventricular junction (AVJ). Heart failure was induced in New Zealand rabbits by disruption of the aortic valve and banding of the abdominal aorta resulting in volume and pressure overload. Laser micro-dissect...

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Other

Date created

24 Oct, 2019

Creator

T Nikolaidou / XJ Cai / RS Stephenson / J Yanni / T Lowe / AJ Atkinson / CB Jones / R Sardar / AF Corno / H Dobrzynski / PJ Withers / JC Jarvis / G Hart / MR Boyett

URL

https://figshare.com/articles/journal_contribution/Congestive_Heart_Failure_Leads_to_Prolongation...

Related subjects

Animals / Atrial Remodeling / Cardiomegaly / Connexin 43 / Disease Models, Animal / Echocardiography / Electrocardiography / Heart Failure / Ion Channels / Male / Myocardium / RNA, Messenger / Rabbits / Ventricular Remodeling / X-Ray Microtomography / Uncategorized

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