Metabolomic profiling of maternal hair suggests rapid development of intrahepatic cholestasis of pregnancy

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Title

Metabolomic profiling of maternal hair suggests rapid development of intrahepatic cholestasis of pregnancy

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Description

Introduction Intrahepatic cholestasis of pregnancy (ICP) is a common maternal liver disease; development can result in devastating consequences, including sudden fetal death and stillbirth. Currently, recognition of ICP only occurs following onset of clinical symptoms. Objective Investigate the maternal hair metabolome for predictive biomarkers of ICP. Methods The maternal hair metabolome (gestational age of sampling between 17 and 41 weeks) of 38 Chinese women with ICP and 46 pregnant cont...

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Date created

13 Jun, 2018

Creator

Jamie V. de Seymour / Stephanie Tu / Xiaoling He / Hua Zhang / Ting-Li Han / Philip N. Baker / Karolina Sulek

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https://figshare.com/articles/journal_contribution/Metabolomic_profiling_of_maternal_hair_suggest...

Related subjects

Science & Technology / Life Sciences & Biomedicine / Endocrinology & Metabolism / Intrahepatic cholestasis of pregnancy / Metabolomics / Hair / Gas chromatography-mass spectrometry / IDENTIFICATION / SPECTROMETRY / DISCOVERY / Uncategorized

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