Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice.

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Title

Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice.

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The University of Auckland Library

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ResearchSpace@Auckland

Description

PurposeThe purpose of this study was to determine the importance of the xCT is a subunit. The cystine/glutamate antiporter is actually system xc-xCT subunit of the cystine/glutamate antiporter in maintaining redox balance by investigating the effects of the loss of xCT on lens transparency and cystine/cysteine balance in the aqueous humour.MethodsC57Bl/6 wild-type and xCT knockout mice at five age groups (6 weeks to 12 months) were used. Lens transparency was examined using a slit-lamp and mo...

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Format

Research paper

Research format

Journal article

Date created

2021-6

Creator

Martis, Renita Maria / Li, Bo / Donaldson, Paul James / Lim, Julie Ching-Hsia

URL

https://hdl.handle.net/2292/56053

Related subjects

06 Biological Sciences / 11 Medical and Health Sciences

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