Cardiac intramural electrical mapping reveals focal delays but no conduction velocity slowing in the peri-infarct region.

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Title

Cardiac intramural electrical mapping reveals focal delays but no conduction velocity slowing in the peri-infarct region.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Altered electrical behavior alongside healed myocardial infarcts (MIs) is associated with increased risk of sudden cardiac death. However, the multidimensional mechanisms are poorly understood and described. This study characterizes, for the first time, the intramural spread of electrical activation in the peri-infarct region of chronic reperfusion MIs. Four sheep were studied 13 wk after antero-apical reperfusion infarction. Extracellular potentials (ECPs) were recorded in a ~20 × 20-mm2 reg...

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Format

Research paper

Research format

Journal article

Date created

2019-10

Creator

Trew, Mark L / Engelman, Zoar J / Caldwell, Bryan J / Lever, Nigel A / LeGrice, Ian J / Smaill, Bruce H

URL

https://hdl.handle.net/2292/56102

Related subjects

Myocardium / Heart Conduction System / Animals / Sheep, Domestic / Myocardial Reperfusion Injury / Myocardial Infarction / Disease Models, Animal / Electrophysiologic Techniques, Cardiac / Cardiac Pacing, Artificial / Predictive Value of Tests / Action Potentials / Time Factors / Female / border zone / conduction / intramural mapping / myocardial infarction / Science & Technology / Life Sciences & Biomedicine / Cardiac & Cardiovascular Systems / Physiology / Peripheral Vascular Disease / Cardiovascular System & Cardiology / EPICARDIAL BORDER ZONE / REENTRANT VENTRICULAR-TACHYCARDIA / ISCHEMIC-HEART-DISEASE / MAGNETIC-RESONANCE / MYOCARDIAL-INFARCTION / RISK STRATIFICATION / MECHANISMS / SUBSTRATE / SCAR / RECONSTRUCTION / 1102 Cardiorespiratory Medicine and Haematology / Clinical Medicine and Science / Cardiovascular / Heart Disease / Heart Disease - Coronary Heart Disease / 0606 Physiology / 1116 Medical Physiology

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