A non-opioid analgesic implant for sustained post-operative intraperitoneal delivery of lidocaine, characterized using an ovine model.

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Title

A non-opioid analgesic implant for sustained post-operative intraperitoneal delivery of lidocaine, characterized using an ovine model.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Appropriate management of post-operative pain is an ongoing challenge in surgical practice. At present, systemic opioid administration is routinely used for analgesia in the post-operative setting. However, due to significant adverse effects and potential for misuse, there is a perceived need for the development of alternative, opioid-sparing treatment modalities. Continuous infusion of local anesthetic into the peritoneum after major abdominal surgery reduces pain and opioid consumption, and...

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Format

Research paper

Research format

Journal article

Date created

2020-12

Creator

Svirskis, Darren / Procter, Georgina / Sharma, Manisha / Bhusal, Prabhat / Dravid, Anusha / MacFater, Wiremu / Barazanchi, Ahmed / Bennet, Laura / Chandramouli, Kaushik / Sreebhavan, Sree / Agarwal, Priyanka / Amirapu, Satya / Hannam, Jacqueline A / Andrews, Gavin P / Hill, Andrew / Jones, David S

URL

https://hdl.handle.net/2292/57363

Related subjects

Animals / Sheep / Humans / Pain, Postoperative / Lidocaine / Analgesics, Non-Narcotic / Analgesics, Opioid / Anesthetics, Local / Co-extrusion / Controlled release / EVA / Opioid-sparing / Pain / Science & Technology / Technology / Engineering, Biomedical / Materials Science, Biomaterials / Engineering / Materials Science / ETHYLENE-VINYL ACETATE / DOUBLE-BLIND / INTRAVENOUS LIDOCAINE / PAIN RELIEF / SYSTEM / INFUSION / RELEASE / SURGERY / MATRIX / TRIAL / 1103 Clinical Sciences / Biomedical / Clinical Medicine and Science / Neurosciences / Patient Safety / Pain Research / Chronic Pain / Bioengineering

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