The Feasibility of Establishing a Morphological Cell Profiling Assay to Assess the Bioactivity of Natural Products

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Title

The Feasibility of Establishing a Morphological Cell Profiling Assay to Assess the Bioactivity of Natural Products

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Description

Morphological cell profiling (MCP) is an assay which quantifies the morphology of cells and cellular components. Changes in the morphology of cells following compound treatment has been shown to assess the bioactivity, and even propose a target of said compound. It is a powerful assay that can be used to assess novel compounds for drug candidature. However, it is currently not transferable between institutions. Thus, this project evaluated the feasibility of establishing an MCP assay at Victo...

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Date created

16 Nov, 2021

Creator

Taylor, Lauren

URL

https://figshare.com/articles/thesis/The_Feasibility_of_Establishing_a_Morphological_Cell_Profili...

Related subjects

Cell Profiling / Morphology / Natural Products / Fluorescence / Microscopy / Flow Cytometry / Assay / Bioactivity / School: School of Biological Sciences / 110199 Medical Biochemistry and Metabolomics not elsewhere classified / 060103 Cell Development, Proliferation and Death / 060106 Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) / 030401 Biologically Active Molecules / 030403 Characterisation of Biological Macromolecules / 030502 Natural Products Chemistry / 970111 Expanding Knowledge in the Medical and Health Sciences / 970103 Expanding Knowledge in the Chemical Sciences / Degree Discipline: Biomedical Science / Degree Level: Masters / Degree Name: Master of Biomedical Science / Medical Biochemistry and Metabolomics not elsewhere classified / Biologically Active Molecules / Characterisation of Biological Macromolecules / Cell Development, Proliferation and Death / Natural Products Chemistry / Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)

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