The Synthesis of Malonganenone Analogues for Antiparasitic Structure-Activity Relationship Analyses

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Title

The Synthesis of Malonganenone Analogues for Antiparasitic Structure-Activity Relationship Analyses

Content partner

Victoria University of Wellington

Collection

Open Access Victoria University of Wellington

Description

The most lethal causative species of malaria, Plasmodium falciparum, has been reported as developing resistance against current antimalarial drugs in South-East Asia. New antimalarial drugs, especially those with novel modes of action, need to be established before resistance spreads.  The marine natural products malonganenones A, B, and C, isolated from the gorgonian Leptogorgia gilchristi, have recently been shown to inhibit P. falciparum parasite growth. Therefore, a library of malonganeno...

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Format

Research paper

Research format

Scholarly text / Thesis

Thesis level

Masters

Date created

2017

Creator

Sarah Andreassend

URL

https://figshare.com/articles/thesis/The_Synthesis_of_Malonganenone_Analogues_for_Antiparasitic_S...

Related subjects

Physical properties of materials / Polymerisation mechanisms / Malaria / Heat shock protein / Prenylated alkaloid / School: School of Chemical and Physical Sciences / Physical Chemistry of Materials / Polymerisation Mechanisms / Expanding Knowledge in the Chemical Sciences / Degree Discipline: Chemistry / Degree Level: Masters / Degree Name: Master of Science

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