Synthesis of Highly Functionalised Furo[3,4-b]pyrans: Towards the Fungal Metabolite (−)-TAN-2483B

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Title

Synthesis of Highly Functionalised Furo[3,4-b]pyrans: Towards the Fungal Metabolite (−)-TAN-2483B

Content partner

Victoria University of Wellington

Collection

Open Access Victoria University of Wellington

Description

Carbohydrate-derived cyclopropanes combine both the stereochemical wealth of carbohydrates and the reactivity of cyclopropanes. A diverse variety of reaction modes for these cyclopropyl carbohydrates can be harnessed for the synthesis of natural products and other targets.  The natural products (−)-TAN-2483A and (−)-TAN-2483B are fungal secondary metabolites displaying a variety of bioactivities such as inhibition of c-src kinase action and parathyroid hormone-induced bone resorption. This th...

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Format

Research paper

Research format

Scholarly text / Thesis

Thesis level

Doctoral

Date created

2014

Creator

Somarathne, R.M. Kalpani K.

URL

https://figshare.com/articles/thesis/Synthesis_of_Highly_Functionalised_Furo_3_4-b_pyrans_Towards...

Related subjects

Biologically active molecules / Natural products and bioactive compounds / Organic chemical synthesis / TAN-2483B / Cyclopropane / Carbonylation / School: School of Chemical and Physical Sciences / Biologically Active Molecules / Natural Products Chemistry / Organic Chemical Synthesis / Expanding Knowledge in the Chemical Sciences / Degree Discipline: Chemistry / Degree Level: Doctoral / Degree Name: Doctor of Philosophy

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