About this item
- Title
- Mechanisms of induction of CD8⁺ T cell responses by dendritic cells
- Content partner
- Victoria University of Wellington
- Collection
- Open Access Victoria University of Wellington
- Description
Splenic CD8α⁺ dendritic cells (DCs) have been described as key antigen presenting cells for the induction of CD8⁺ T cell responses to circulating antigen. This is through a heightened capacity to acquire and present the antigens via the process of cross-presentation, expression of high levels of the co-stimulatory and adhesion molecules required to stimulate CD8⁺ T cells, and the capacity to release high levels of the cytokines required to drive differentiation of CD8⁺ T cells into cytotoxic ...
- Format
- Research paper
- Research format
- Scholarly text / Thesis
- Thesis level
- Doctoral
- Date created
- 2014
- Creator
- Osmond, Taryn Louise
- URL
- https://figshare.com/articles/thesis/Mechanisms_of_induction_of_CD8_T_cell_responses_by_dendritic...
- Related subjects
- Biochemistry and cell biology not elsewhere classified / Medical biochemistry and metabolomics not elsewhere classified / Medical microbiology not elsewhere classified / Dendritic cells / CD8⁺ T cells / Cross-priming / School: School of Biological Sciences / Biochemistry and Cell Biology not elsewhere classified / Medical Biochemistry and Metabolomics not elsewhere classified / Medical Microbiology not elsewhere classified / Expanding Knowledge in the Biological Sciences / Expanding Knowledge in the Medical and Health Sciences / Degree Discipline: Biomedical Science / Degree Level: Doctoral / Degree Name: Doctor of Philosophy
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