Maternal Mid-Gestation Cytokine Dysregulation in Mothers of Children with Autism Spectrum Disorder.

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Title

Maternal Mid-Gestation Cytokine Dysregulation in Mothers of Children with Autism Spectrum Disorder.

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The University of Auckland Library

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ResearchSpace@Auckland

Description

Autism spectrum disorder (ASD) is a developmental disorder characterised by deficits in social interactions and communication, with stereotypical and repetitive behaviours. Recent evidence suggests that maternal immune dysregulation may predispose offspring to ASD. Independent samples t-tests revealed downregulation of IL-17A concentrations in cases, when compared to controls, at both 15 weeks (p = 0.02), and 20 weeks (p = 0.02), which persisted at 20 weeks following adjustment for confoundin...

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Format

Research paper

Research format

Journal article

Date created

2021-09-09

Creator

Casey, S / Carter, M / Looney, AM / Livingstone, V / Moloney, G / O'Keeffe, GW / Taylor, RS / Kenny, LC / McCarthy, FP / McCowan, LME / Thompson, JMD / Murray, DM / SCOPE Consortium

URL

https://hdl.handle.net/2292/59135

Related subjects

SCOPE Consortium / Autism spectrum disorder / Cytokine / IL-17A / Inflammation / Maternal immune activation / Brain Disorders / Intellectual and Developmental Disabilities (IDD) / Pediatric / Mental Health / Autism / 2.1 Biological and endogenous factors / Reproductive health and childbirth / Social Sciences / Psychology, Developmental / Psychology / FETAL-BRAIN DEVELOPMENT / IMMUNE ACTIVATION / CESAREAN-SECTION / PRENATAL INFECTION / AMNIOTIC-FLUID / RISK-FACTOR / PREGNANCY / BEHAVIOR / 13 Education / 17 Psychology and Cognitive Sciences

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