Comparison of Sinus Deposition from an Aqueous Nasal Spray and Pressurised MDI in a Post-Endoscopic Sinus Surgery Nasal Replica.

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Title

Comparison of Sinus Deposition from an Aqueous Nasal Spray and Pressurised MDI in a Post-Endoscopic Sinus Surgery Nasal Replica.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

BackgroundOptimising intranasal distribution and retention of topical therapy is essential for effectively managing patients with chronic rhinosinusitis, including those that have had functional endoscopic sinus surgery (FESS). This study presents a new technique for quantifying in vitro experiments of fluticasone propionate deposition within the sinuses of a 3D-printed model from a post-FESS patient.MethodsCircular filter papers were placed on the sinus surfaces of the model. Deposition of f...

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Format

Research paper

Research format

Journal article

Date created

2022-02-08

Creator

Siu, Joey / van Strien, James / Campbell, Rosa / Roberts, Paul / Tingle, Malcolm Drummond / Inthavong, Kiao / Douglas, Richard George

URL

https://hdl.handle.net/2292/59126

Related subjects

Paranasal Sinuses / Humans / Glucocorticoids / Administration, Inhalation / Drug Compounding / Metered Dose Inhalers / Tissue Distribution / Models, Anatomic / Middle Aged / Female / Nasal Sprays / Printing, Three-Dimensional / Fluticasone / Transanal Endoscopic Surgery / Administration, intranasal / Administration, topical / Drug delivery systems / Nasal airflow, Nasal cavity, Nasal spray / Sinusitis / Science & Technology / Physical Sciences / Life Sciences & Biomedicine / Chemistry, Multidisciplinary / Pharmacology & Pharmacy / Chemistry / Administration / intranasal / topical / Nasal airflow / Nasal cavity / Nasal spray / AIR-FLOW / PARTICLE DEPOSITION / DRUG-DELIVERY / IN-VITRO / QUANTIFICATION / ATOMIZATION / DEVICES / CAVITY / PUMPS / 1115 Pharmacology and Pharmaceutical Sciences

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