Proteomic Characterisation of Pateamine A Treatment of Glioblastoma

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Title

Proteomic Characterisation of Pateamine A Treatment of Glioblastoma

Content partner

Victoria University of Wellington

Collection

Open Access Victoria University of Wellington

Description

<b>Pateamine A is a potent inhibitor of eukaryotic translation initiation factor eIF4A, with potential application in cancer treatment. Glioblastoma is a highly aggressive and clinically challenging type of brain cancer. Existing evidence shows glioblastoma exhibit an abnormal energy metabolism, and there is also evidence that pateamine A causes alterations in the energy metabolism of other cancer cell lines. This research investigates the effects of eIF4A inhibition on biological pathways in...

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Format

Research paper

Research format

Scholarly text / Thesis

Thesis level

Masters

Date created

2022

Creator

Pot, Veronica

URL

https://figshare.com/articles/thesis/Proteomic_Characterisation_of_Pateamine_A_Treatment_of_Gliob...

Related subjects

Proteomics and intermolecular interactions (excl. medical proteomics) / pateamine / glioblastoma / proteomics / cycloheximide / gene ontology / eIF4A / translation inhibition / School: School of Biological Sciences / Unit: Ferrier Research Institute / Proteomics and Intermolecular Interactions (excl. Medical Proteomics) / Expanding knowledge in the biological sciences / Degree Discipline: Biology / Degree Level: Masters / Degree Name: Master of Drug Discovery and Development

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