Artificial Cell Membrane Polymersome-Based Intranasal Beta Spike Formulation as a Second Generation Covid-19 Vaccine

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Title

Artificial Cell Membrane Polymersome-Based Intranasal Beta Spike Formulation as a Second Generation Covid-19 Vaccine

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Description

Current parenteral coronavirus disease 2019 (Covid-19) vaccines inadequately protect against infection of the upper respiratory tract. Additionally, antibodies generated by wild type (WT) spike-based vaccines poorly neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. To address the need for a second-generation vaccine, we have initiated a preclinical program to produce and evaluate a potential candidate. Our vaccine consists of recombinant Beta spike protein coad...

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Format

Other

Date created

12 Oct, 2022

Creator

Jian Hang Lam / Devendra Shivhare / Teck Wan Chia / Suet Li Chew / Gaurav Sinsinbar / Ting Yan Aw / Siamy Wong / Shrinivas Venkataraman / Francesca Wei Inng Lim / Pierre Vandepapeliere / Madhavan Nallani

URL

https://figshare.com/articles/journal_contribution/Artificial_Cell_Membrane_Polymersome-Based_Int...

Related subjects

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