Model-based PEEP titration versus standard practice in mechanical ventilation: A randomised controlled trial

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Title

Model-based PEEP titration versus standard practice in mechanical ventilation: A randomised controlled trial

Content partner

University of Canterbury Library

Collection

UC Research Repository

Description

Background: Positive end-expiratory pressure (PEEP) at minimum respiratory elastance during mechanical ventilation (MV) in patients with acute respiratory distress syndrome (ARDS) may improve patient care and outcome. The Clinical utilisation of respiratory elastance (CURE) trial is a two-arm, randomised controlled trial (RCT) investigating the performance of PEEP selected at an objective, model-based minimal respiratory system elastance in patients with ARDS. Methods and design: The CURE RCT...

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Format

Research paper

Research format

Journal article

Date created

2020

Creator

Kim KT / Morton S / Howe S / Chiew YS / Desaive T / Benyo B / Szlavecz A / Moeller K / Shaw, Geoff / Knopp, Jennifer / Docherty, Paul / Pretty, Christopher / Chase, Geoff

URL

https://hdl.handle.net/10092/102041

Related subjects

Respiratory System / Humans / Respiratory Distress Syndrome, Adult / Oxygen / Breath Tests / Respiration, Artificial / Positive-Pressure Respiration / Oxygen Consumption / Computer-Aided Design / Middle Aged / Female / Male / Randomized Controlled Trials as Topic / Clinical Trials, Phase II as Topic / Ventilator-Induced Lung Injury / Outcome Assessment, Health Care / ARDS / mechanical ventilation / pulmonary mechanics / RCT / PEEP titration / Cardiorespiratory Medicine and Haematology / Clinical Sciences / Biomedical and clinical sciences / Clinical sciences / Intensive care / Cardiovascular medicine and haematology / Respiratory diseases / Engineering / Biomedical engineering / Computational physiology

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