Simulation of Calcium Dynamics in Realistic Three-Dimensional Domains.

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Title

Simulation of Calcium Dynamics in Realistic Three-Dimensional Domains.

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The University of Auckland Library

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Description

The cytosolic concentration of free calcium ions ([Ca2+]) is an important intracellular messenger in most cell types, and the spatial distribution of [Ca2+] is often critical. In a salivary gland acinar cell, a polarised epithelial cell, whose principal function is to transport water and thus secrete saliva, [Ca2+] controls the secretion of primary saliva, but increases in [Ca2+] are localised to the apical regions of the cell. Hence, any quantitative explanation of how [Ca2+] controls saliva...

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Format

Research paper

Research format

Journal article

Date created

2022-10-11

Creator

Sneyd, James / Rugis, John / Su, Shan / Suresh, Vinod / Wahl, Amanda M / Yule, David I

URL

https://hdl.handle.net/2292/62158

Related subjects

Ions / Calcium / Water / Ion Channels / Acinar Cells / calcium dynamics / finite-element methods / saliva secretion / three-dimensional simulations / Dental/Oral and Craniofacial Disease / 1 Underpinning research / 1.1 Normal biological development and functioning / 0601 Biochemistry and Cell Biology

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