Using the Lens Paradox to Optimize an In Vivo MRI-Based Optical Model of the Aging Human Crystalline Lens.

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Title

Using the Lens Paradox to Optimize an In Vivo MRI-Based Optical Model of the Aging Human Crystalline Lens.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

PurposeTo optimize our in vivo magnetic resonance imaging (MRI)-based optical model of the human crystalline lens, developed with a small group of young adults, for a larger cohort spanning a wider age range.MethodsSubjective refraction and ocular biometry were measured in 57 healthy adults ages 18 to 86 years who were then scanned using 3T clinical magnetic resonance imaging (MRI) to obtain lens gradient of refractive index (GRIN) and geometry measurements. These parameters were combined wit...

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Format

Research paper

Research format

Journal article

Date created

2020-07

Creator

Lie, Alyssa L / Pan, Xingzheng / White, Thomas W / Donaldson, Paul J / Vaghefi, Ehsan

URL

https://hdl.handle.net/2292/62460

Related subjects

Lens, Crystalline / Humans / Magnetic Resonance Imaging / Refraction, Ocular / Biometry / Aging / Adolescent / Adult / Aged / Aged, 80 and over / Middle Aged / Young Adult / clinical observational study / crystalline lens / gradient of refractive index / in vivo / lens paradox / lens physiological optics / optical modeling / Clinical Research / Eye Disease and Disorders of Vision / Biomedical Imaging / Science & Technology / Life Sciences & Biomedicine / Ophthalmology / REFRACTIVE-INDEX DISTRIBUTION / AGE-RELATED-CHANGES / GRADIENT-INDEX / HUMAN-EYE / ADULT-POPULATION / ADAPTIVE MODEL / WATER-CONTENT / POWER / SHAPE / CURVATURE / 0903 Biomedical Engineering / 1113 Opthalmology and Optometry

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