Next-generation sequencing as an advanced supplementary tool for the diagnosis of pathogens in lower respiratory tract infections: An observational trial in Xi'an, China.

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Title

Next-generation sequencing as an advanced supplementary tool for the diagnosis of pathogens in lower respiratory tract infections: An observational trial in Xi'an, China.

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The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

The application of next-generation sequencing (NGS) in routine clinical analysis is still limited. The significance of NGS in the identification of pathogens of lower respiratory tract infection should be assessed as part of routine clinical bacterial examinations and chest imaging results. In the present study, the alveolar lavage fluid samples of 30 patients (25 males and 5 females, aged 19-92 years old, with a median age of 62) were examined by routine bacterial culture and NGS, and the re...

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Format

Research paper

Research format

Journal article

Date created

2022-02

Creator

Shao, Jie / Hassouna, Amira / Wang, Yaqin / Zhang, Ruirui / Zhen, Lifang / Li, Ruidan / Chen, Mingli / Liu, Chengjie / Wang, Xiangye / Zhang, Mingming / Wang, Peng / Yuan, Shenghua / Chen, Jie / Lu, Jun

URL

https://hdl.handle.net/2292/63000

Related subjects

bacterial culture / bronchoalveolar lavage fluid / diagnosis / next-generation sequencing / pulmonary infection / Lung / Biotechnology / Infectious Diseases / Prevention / 4.1 Discovery and preclinical testing of markers and technologies / 4.2 Evaluation of markers and technologies / 4 Detection, screening and diagnosis / Infection / 3 Good Health and Well Being / Science & Technology / Life Sciences & Biomedicine / Medicine, Research & Experimental / Research & Experimental Medicine / COMMUNITY-ACQUIRED PNEUMONIA / BRONCHOALVEOLAR LAVAGE / CHILDREN / METAGENOMICS / BRONCHOSCOPY / VIRUSES / DISEASE / BURDEN / ADULTS / PCR

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