Potential for treatment of neurodegenerative diseases with natural products or synthetic compounds that stabilize microtubules

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Title

Potential for treatment of neurodegenerative diseases with natural products or synthetic compounds that stabilize microtubules

Content partner

Victoria University of Wellington

Collection

Open Access Victoria University of Wellington

Description

No effective therapeutics to treat neurodegenerative diseases exist, despite significant attempts to find drugs that can reduce or rescue the debilitating symptoms of tauopathies such as Alzheimer’s disease, Parkinson’s disease, frontotemporal dementia, amyotrophic lateral sclerosis, or Pick’s disease. A number of in vitro and in vivo models exist for studying neurodegenerative diseases, including cell models employing induced-pluripotent stem cells, cerebral organoids, and animal models of d...

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Format

Research paper

Research format

Scholarly text / Journal article

Date created

2020

Creator

John Miller / V Das

URL

https://figshare.com/articles/journal_contribution/Potential_for_treatment_of_neurodegenerative_d...

Related subjects

Pharmacology and pharmaceutical sciences not elsewhere classified / Alzheimer's disease / davunetide / epothilone D / microtubule stabilizing agents / parkinson's disease / tauopathies / triazolopyrimidine / Alzheimer Disease / Animals / Biological Products / Humans / Microtubules / Neurodegenerative Diseases / Tauopathies / tau Proteins / Brain Disorders / Dementia / Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) / Neurosciences / Acquired Cognitive Impairment / Neurodegenerative / Frontotemporal Dementia (FTD) / Aging / Stem Cell Research / Alzheimer's Disease / Rare Diseases / Development of treatments and therapeutic interventions / .1 Pharmaceuticals / Neurological / Medicinal & Biomolecular Chemistry / Pharmacology and pharmaceutical sciences / Pharmacology and Pharmaceutical Sciences not elsewhere classified

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