sAPPα’s Regulation of the Memory Molecule, CaMKIIα

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Title

sAPPα’s Regulation of the Memory Molecule, CaMKIIα

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Synaptic plasticity is a phenomenon underlying the ability of the central nervous system to make and retain memories. It requires the dynamic regulation of glutamate receptor expression and plasticity-related proteins. Recent work in the Williams laboratory has identified neuroprotective and plasticity-enhancing effects of the secreted amyloid precursor protein-alpha (sAPPα); positing this molecule as a potential therapeutic for Alzheimer’s Disease, a neurodegenerative disorder affecting plas...

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Format

Research paper

Research format

Scholarly text / Thesis

Thesis level

Masters

Date created

2023

Creator

Wales-Earl, Lucy

URL

https://hdl.handle.net/10523/15409

Related subjects

New Zealand / sAPPa / CaMKIIa / Alzheimer's Disease / neuroprotective / plasticity / synaptic / molecular / Calmodulin Dependent Kinase Two Alpha / Secreted amyloid precursor protein alpha

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