Trace biomarkers associated with spontaneous preterm birth from the maternal serum metabolome of asymptomatic nulliparous women - parallel case-control studies from the SCOPE cohort.

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Title

Trace biomarkers associated with spontaneous preterm birth from the maternal serum metabolome of asymptomatic nulliparous women - parallel case-control studies from the SCOPE cohort.

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Prediction of spontaneous preterm birth (sPTB) in asymptomatic women remains a great challenge; accurate and reproducible screening tools are still not available in clinical practice. We aimed to investigate whether the maternal serum metabolome together with clinical factors could be used to identify asymptomatic women at risk of sPTB. We conducted two case-control studies using gas chromatography-mass spectrometry to analyse maternal serum samples collected at 15- and 20-weeks' gestation fr...

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Format

Research paper

Research format

Journal article

Date created

2019-09

Creator

Souza, Renato T / McKenzie, Elizabeth J / Jones, Beatrix / de Seymour, Jamie V / Thomas, Melinda M / Zarate, Erica / Han, Ting Li / McCowan, Lesley / Sulek, Karolina / Villas-Boas, Silas / Kenny, Louise C / Cecatti, José G / Baker, Philip N

URL

https://hdl.handle.net/2292/64760

Related subjects

Humans / Premature Birth / Case-Control Studies / Maternal Age / Pregnancy / Adult / Infant, Newborn / Female / Mass Spectrometry / Metabolome / Biomarkers / Perinatal Period - Conditions Originating in Perinatal Period / Pediatric / 4 Detection, screening and diagnosis / 4.2 Evaluation of markers and technologies / Reproductive health and childbirth / 3 Good Health and Well Being / Science & Technology / Multidisciplinary Sciences / Science & Technology - Other Topics / LONG-TERM OUTCOMES / CERVICAL LENGTH / FETAL FIBRONECTIN / GESTATIONAL-AGE / LUNG-CANCER / TIME TRENDS / RISK / MARKERS / TECHNOLOGIES / 1114 Paediatrics and Reproductive Medicine / Clinical / Clinical Medicine and Science

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