Phosphatidylcholine-Specific Phospholipase C as a Promising Drug Target

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Title

Phosphatidylcholine-Specific Phospholipase C as a Promising Drug Target

Content partner

The University of Auckland Library

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ResearchSpace@Auckland

Description

Phosphatidylcholine-specific phospholipase C (PC-PLC) is an enzyme that catalyzes the formation of the important secondary messengers phosphocholine and diacylglycerol (DAG) from phosphatidylcholine. Although PC-PLC has been linked to the progression of many pathological conditions, including cancer, atherosclerosis, inflammation and neuronal cell death, studies of PC-PLC on the protein level have been somewhat neglected with relatively scarce data. To date, the human gene expressing PC-PLC h...

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Format

Research paper

Research format

Journal article

Creator

Eurtivong, Chatchakorn / Leung, Euphemia / Sharma, Nabangshu / Leung, Ivanhoe KH / Reynisson, Jóhannes

URL

https://hdl.handle.net/2292/65373

Related subjects

3404 Medicinal and Biomolecular Chemistry / 3405 Organic Chemistry / 34 Chemical Sciences / Genetics / Aging / Cancer / 0304 Medicinal and Biomolecular Chemistry / 0305 Organic Chemistry / 0307 Theoretical and Computational Chemistry

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