Detecting localised prostate cancer using radiomic features in PSMA PET and multiparametric MRI for biologically targeted radiation therapy

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Title

Detecting localised prostate cancer using radiomic features in PSMA PET and multiparametric MRI for biologically targeted radiation therapy

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Background Prostate-Specifc Membrane Antigen (PSMA) PET/CT and multiparametric MRI (mpMRI) are wellestablished modalities for identifying intra-prostatic lesions (IPLs) in localised prostate cancer. This study aimed to investigate the use of PSMA PET/CT and mpMRI for biologically targeted radiation therapy treatment planning by: (1) analysing the relationship between imaging parameters at a voxel-wise level and (2) assessing the performance of radiomic-based machine learning models to predict...

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Format

Research paper

Research format

Journal article

Date created

2023-04

Creator

Chan, Tsz Him / Haworth, Annette / Wang, Alan / Osanlouy, Mahyar / Williams, Scott / Mitchell, Catherine / Hofman, Michael S / Hicks, Rodney J / Murphy, Declan G / Reynolds, Hayley M

URL

https://hdl.handle.net/2292/66173

Related subjects

Multiparametric MRI / PSMA PET/CT / Prostate cancer / Radiation therapy / Radiomics / 32 Biomedical and Clinical Sciences / 3202 Clinical Sciences / 3211 Oncology and Carcinogenesis / Cancer / Urologic Diseases / Bioengineering / Aging / Biomedical Imaging / 4 Detection, screening and diagnosis / 4.4 Population screening / 4.2 Evaluation of markers and technologies / 3 Good Health and Well Being / Science & Technology / Life Sciences & Biomedicine / Radiology, Nuclear Medicine & Medical Imaging / PSMA PET / CT / POSITRON-EMISSION-TOMOGRAPHY / DIAGNOSIS / SYSTEM / 1101 Medical Biochemistry and Metabolomics / 1103 Clinical Sciences / 1112 Oncology and Carcinogenesis

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