Double Sigmoid Model for Fitting Fatigue Profiles in Mouse Fast- and Slow-Twitch Muscle

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Title

Double Sigmoid Model for Fitting Fatigue Profiles in Mouse Fast- and Slow-Twitch Muscle

Content partner

Auckland University of Technology

Collection

Tuwhera

Description

We present a curve-fitting approach that permits quantitative comparisons of fatigue profiles obtained with different stimulation protocols in isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles of mice. Profiles from our usual stimulation protocol (125 Hz for 500 ms, evoked once every second for 100-300 s) could be fitted by single-term functions (sigmoids or exponentials) but not by a double exponential. A clearly superior fit, as confirmed by the Akaiki Info...

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Format

Research paper

Research format

Journal article

Date created

2008

Creator

Cairns, SP / Robinson, D / Loiselle, DS

URL

https://openrepository.aut.ac.nz/handle/10292/17189

Related subjects

Science & Technology / Life Sciences & Biomedicine / Physiology / MAMMALIAN SKELETAL-MUSCLE / INORGANIC-PHOSPHATE / FORCE DECLINE / TETANIC FORCE / SOLEUS MUSCLE / RAT HINDLIMB / MOTOR UNITS / P-I / STIMULATION / FIBERS / 3208 Medical Physiology / 32 Biomedical and Clinical Sciences / Neurosciences / 1 Underpinning research / 1.1 Normal biological development and functioning / 0606 Physiology / 1106 Human Movement and Sports Sciences / 1116 Medical Physiology / 3109 Zoology / 3208 Medical physiology / 4207 Sports science and exercise / Animals / Electric Stimulation / Female / Mice / Models, Animal / Models, Biological / Muscle Fatigue / Muscle Fibers, Fast-Twitch / Muscle Fibers, Slow-Twitch / Muscle, Skeletal

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© 2008 The Authors. Free access.

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