Circulatory miRNAs as Correlates of Elevated Intra-Pancreatic Fat Deposition in a Mixed Ethnic Female Cohort: The TOFI Asia Study

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Title

Circulatory miRNAs as Correlates of Elevated Intra-Pancreatic Fat Deposition in a Mixed Ethnic Female Cohort: The TOFI Asia Study

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

Ectopic lipid accumulation, including intra-pancreatic fat deposition (IPFD), exacerbates type 2 diabetes risk in susceptible individuals. Dysregulated circulating microRNAs (miRNAs) have been identified as correlating with clinical measures of pancreatitis, pancreatic cancer and type 1 diabetes. The aim of the current study was therefore to examine the association between circulating abundances of candidate miRNAs, IPFD and liver fat deposition as quantified using magnetic resonance imaging ...

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Format

Research paper

Research format

Journal article

Date created

2023-09

Creator

Ramzan, Farha / Sequeira-Bisson, Ivana R / Lu, Louise W / Mitchell, Cameron J / D'Souza, Randall F / Vickers, Mark H / Poppitt, Sally D / Cameron-Smith, David

URL

https://hdl.handle.net/2292/67391

Related subjects

IPFD / biomarker / ectopic / liver fat / miR-21-3p / miR-320a-5p / miRNA / 3404 Medicinal and Biomolecular Chemistry / 34 Chemical Sciences / Pancreatic Cancer / Clinical Research / Liver Disease / Rare Diseases / Digestive Diseases / Nutrition / Cancer / Biomedical Imaging / Prevention / Biotechnology / Diabetes / 2.1 Biological and endogenous factors / 4.1 Discovery and preclinical testing of markers and technologies / 4 Detection, screening and diagnosis / 2 Aetiology / Metabolic and endocrine / Oral and gastrointestinal / Science & Technology / Life Sciences & Biomedicine / Physical Sciences / Biochemistry & Molecular Biology / Chemistry, Multidisciplinary / Chemistry / MICRORNAS / PANCREATITIS / ACCUMULATION / GLUCOSE / 0399 Other Chemical Sciences / 0604 Genetics / 0699 Other Biological Sciences / 3101 Biochemistry and cell biology / 3107 Microbiology

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