COVID-19 infection activates genetically predisposed risk pathways in lungs to escalate T1D development

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Title

COVID-19 infection activates genetically predisposed risk pathways in lungs to escalate T1D development

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The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

After the COVID-19 pandemic started in 2019, it quickly spread and infected millions of people causing substantial economic and social disruptions worldwide. Type 1 Diabetes (T1D) incident rates were reported to increase in many countries unexpectedly. Accumulated evidence supported the elevated rates were promoted by the pandemic and the underlying mechanisms remained elusive. We propose the hypothesis that genetic predisposition hyperactivates COVID-19 respiratory viral immune responses in ...

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Format

Research paper

Research format

Journal article

Date created

2024-02

Creator

Ho, Daniel / O'Sullivan, Justin M

URL

https://hdl.handle.net/2292/67693

Related subjects

32 Biomedical and Clinical Sciences / 3204 Immunology / Diabetes / Prevention / Pediatric Research Initiative / Infectious Diseases / Pneumonia & Influenza / Lung / Pediatric / Autoimmune Disease / 2.1 Biological and endogenous factors / 2.2 Factors relating to the physical environment / 2 Aetiology / Infection / 3 Good Health and Well Being / 11 Medical and Health Sciences

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