Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T

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Title

Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Aims N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity troponin T (hs-TnT) and soluble suppression of tumorigenesis-2 (sST2) predict outcome in chronic heart failure (HF). We assessed the influence of age on circulating levels and prognostic significance of these biomarkers. Methods and results Individual data from 5301 patients with chronic HF and NT-proBNP, hs-TnT, and sST2 data were evaluated. Patients were stratified according to age: <60 years (n = 1332, 25%), 60-69...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2020-11

Creator

Aimo, Alberto / Januzzi, James L. / Vergaro, Giuseppe / Richards, A. Mark / Lam, Carolyn S. P. / Latini, Roberto / Anand, Inder S. / Cohn, Jay N. / Ueland, Thor / Gullestad, Lars / Aukrust, Pal / Brunner-La Rocca, Hans-Peter / Bayes-Genis, Antoni / Lupon, Josep / de Boer, Rudolf A. / Takeishi, Yasuchika / Egstrup, Michael / Gustafsson, Ida / Gaggin, Hanna K. / Eggers, Kai M. / Huber, Kurt / Gamble, Greg D. / Ling, Lieng H. / Leong, Kui Tong Gerard / Yeo, Poh Shuah Daniel / Ong, Hean Yee / Jaufeerally, Fazlur / Ng, Tze P. / Troughton, Richard / Doughty, Robert N. / Passino, Claudio / Emdin, Michele

URL

https://hdl.handle.net/10523/18548

Related subjects

Cardiac & Cardiovascular Systems / Cardiovascular System & Cardiology / Life Sciences & Biomedicine / Science & Technology

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