Genetic testing for misclassified monogenic diabetes in Māori and Pacific peoples in Aōtearoa New Zealand with early-onset type 2 diabetes

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Title

Genetic testing for misclassified monogenic diabetes in Māori and Pacific peoples in Aōtearoa New Zealand with early-onset type 2 diabetes

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Monogenic diabetes accounts for 1-2% of diabetes cases yet is often misdiagnosed as type 2 diabetes. The aim of this study was to examine in Māori and Pacific adults clinically diagnosed with type 2 diabetes within 40 years of age, (a) the prevalence of monogenic diabetes in this population (b) the prevalence of beta-cell autoantibodies and (c) the pre-test probability of monogenic diabetes. Targeted sequencing data of 38 known monogenic diabetes genes was analyzed in 199 Māori and Pacific pe...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2023-05-10

Creator

Toomata, Zanetta / Leask, Megan / Krishnan, Mohanraj / Cadzow, Murray / Dalbeth, Nicola / Stamp, Lisa K / de Zoysa, Janak / Merriman, Tony / Wilcox, Phillip / Dewes, Ofa / Murphy, Rinki

URL

https://hdl.handle.net/10523/16990

Related subjects

Adult / Diabetes Mellitus, Type 2 - diagnosis / Diabetes Mellitus, Type 2 - epidemiology / Diabetes Mellitus, Type 2 - genetics / Genetic Testing / Humans / Maori People / New Zealand - epidemiology

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