Repurposing ebselen as an inhalable dry powder to treat respiratory tract infections

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Title

Repurposing ebselen as an inhalable dry powder to treat respiratory tract infections

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Respiratory tract infections (RTIs) are one of the leading causes of death globally, lately exacerbated by the increasing prevalence of antimicrobial resistance. While antimicrobial resistance could be overcome by developing new antimicrobial agents, the use of a safe repurposed agent having potent antimicrobial activity against various RTIs can be an efficient and cost-effective alternative to overcome the long and complex process of developing and testing new drugs. Ebselen, a synthetic org...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2024-02

Creator

Saha, Tushar / Lyons, Nikita / Yue Yung, Deborah Bow / Quiñones-Mateu, Miguel E / Pletzer, Daniel / Das, Shyamal C

URL

https://hdl.handle.net/10523/22517

Related subjects

Administration, Inhalation / Anti-Infective Agents - therapeutic use / Drug Repositioning / Dry Powder Inhalers - methods / Humans / Isoindoles / Leucine / Organoselenium Compounds / Particle Size / Powders - chemistry / Respiratory Aerosols and Droplets / Respiratory Tract Infections - drug therapy / Staphylococcus aureus

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