Appl1, Sortilin and Syndecan-1 immunohistochemistry on intraductal carcinoma of the prostate provides evidence of retrograde spread

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Title

Appl1, Sortilin and Syndecan-1 immunohistochemistry on intraductal carcinoma of the prostate provides evidence of retrograde spread

Content partner

University of Otago

Collection

Otago University Research Archive

Description

The presence of intraductal carcinoma of the prostate (IDCP) correlates with late-stage disease and poor outcomes for patients with prostatic adenocarcinoma, but the accurate and reliable staging of disease severity remains challenging. Immunohistochemistry (IHC) has been utilised to overcome problems in assessing IDCP morphology, but the current markers have only demonstrated limited utility in characterising the complex biology of this lesion. In a retrospective study of a cohort of patient...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2023-10-01

Creator

Sorvina, Alexandra / Martini, Carmela / Prabhakaran, Sarita / Logan, Jessica M. / S-Y. Ung, Benjamin / Moore, Courtney / Johnson, Ian R.D. / Lazniewska, Joanna / Tewari, Prerna / Malone, Victoria / Brooks, Robert D. / Hickey, Shane M. / Caruso, Maria C. / Klebe, Sonja / Karageorgos, Litsa / O'Leary, John J. / Delahunt, Brett / Samaratunga, Hemamali / Brooks, Doug A.

URL

https://hdl.handle.net/10523/20900

Related subjects

Appl1 / IDCP / IHC / immunohistochemistry / Intraductal carcinoma of the prostate / retrograde spread / Sortilin / Syndecan-1

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