Research paper

Nitrates in combination with hydralazine in cardiorenal syndrome: a randomized controlled proof-of-concept study

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Title
Nitrates in combination with hydralazine in cardiorenal syndrome: a randomized controlled proof-of-concept study
Content partner
University of Otago
Collection
Otago University Research Archive
Description

Aims Cardiorenal syndrome (CRS) is a common problem of great morbidity and mortality. Hydralazine-isosorbide dinitrate (H-ISDN) may be used in renal failure and may improve exercise capacity in heart failure (HF). Our proof-of-concept study aimed to evaluate early evidence of efficacy, safety, and feasibility of H-ISDN compared with standard of care in CRS. Methods and results This multi-centre, single-blind, randomized trial in Singapore enrolled CRS patients, defined as chronic HF with conc...

Format
Research paper
Research format
Scholarly text / Journal article
Thesis level
Article
Date created
2020-12
Creator
Lim, Shir Lynn / Gandhi, Mihir / Woo, Kai Lee / Chua, Horng Ruey / Lim, Yoke Ching / Sim, David K. L. / Lee, Sheldon S. G. / Teoh, Yee Leong / Richards, Arthur Mark / Lam, Carolyn S. P.
URL
https://hdl.handle.net/10523/17987
Related subjects
Cardiac & Cardiovascular Systems / Cardiovascular System & Cardiology / Life Sciences & Biomedicine / Science & Technology

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