Randomized, Controlled, Double-Masked, Multicenter, Pilot Study Evaluating Safety and Efficacy of Intranasal Neurostimulation for Dry Eye Disease

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Title

Randomized, Controlled, Double-Masked, Multicenter, Pilot Study Evaluating Safety and Efficacy of Intranasal Neurostimulation for Dry Eye Disease

Content partner

The University of Auckland Library

Collection

ResearchSpace@Auckland

Description

PurposeWe assess the safety and effectiveness of intranasal neurostimulation to promote tear production via the nasolacrimal pathway in subjects with dry eye disease.MethodsA multicenter, randomized, controlled, double-masked pilot study was conducted in adults with dry eye diagnosis and at least one eye with corneal fluorescein staining ≥2 in at least one region or a sum of all regions ≥5 (National Eye Institute grading), basal Schirmer test score ≤10 mm, a cotton-swab stimulated Schirmer sc...

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Format

Research paper

Research format

Journal article

Creator

Cohn, Geoffrey S / Corbett, Dean / Tenen, Abi / Coroneo, Minas / McAlister, James / Craig, Jennifer P / Gray, Trevor / Kent, David / Murray, Neil / Petsoglou, Con / Baba, Stephanie N / Holland, Edward J

URL

https://hdl.handle.net/2292/69436

Related subjects

Nasal Mucosa / Tears / Humans / Dry Eye Syndromes / Transcutaneous Electric Nerve Stimulation / Prospective Studies / Pilot Projects / Double-Blind Method / Protective Devices / Adult / Aged / Middle Aged / Female / Male / Slit Lamp Microscopy / 32 Biomedical and Clinical Sciences / 3212 Ophthalmology and Optometry / Patient Safety / Eye Disease and Disorders of Vision / Clinical Trials and Supportive Activities / Clinical Research / Science & Technology / Life Sciences & Biomedicine / Ophthalmology / dry eye disease / EPIDEMIOLOGY / STIMULATION / 1113 Opthalmology and Optometry / Clinical / Clinical Medicine and Science / Prevention / 06 Biological Sciences / 11 Medical and Health Sciences

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