The quest to deliver high-dose rifampicin: can the inhaled approach help?

About this item

Title

The quest to deliver high-dose rifampicin: can the inhaled approach help?

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Tuberculosis (TB) is a global health problem that poses a challenge to global treatment programs. Rifampicin is a potent and highly effective drug for TB treatment; however, higher oral doses than the standard dose (10 mg/kg/day) rifampicin may offer better efficacy in TB treatment. High oral dose rifampicin is not implemented in anti-TB regimens yet and requires about a 3-fold increase in dose for increased efficacy. We discuss inhaled delivery of rifampicin as an alternative or adjunct to o...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2024

Creator

Khadka, Prakash / Dummer, Jack / Hill, Philip C / Das, Shyamal C

URL

https://hdl.handle.net/10523/23090

Related subjects

Administration, Inhalation / Animals / Antitubercular Agents / Dry Powder Inhalers / Humans / Lung / Rifampin - therapeutic use / Tuberculosis - drug therapy

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