Research paper

Colchicine: the good, the bad, the ugly and how to minimize the risks

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Title
Colchicine: the good, the bad, the ugly and how to minimize the risks
Content partner
University of Otago
Collection
Otago University Research Archive
Description

Colchicine has an important role in managing various conditions, including gout, familial Mediterranean fever, amyloidosis, Behçet's syndrome, recurrent pericarditis and calcium pyrophosphate deposition disease. The adverse effect profile of colchicine is well understood. However, due to its narrow therapeutic index, colchicine has been associated with overdose and fatalities. When ingested in toxic amounts, the mainstay of management is supportive care. Strategies to minimize the risk of col...

Format
Research paper
Research format
Scholarly text / Journal article
Thesis level
Article
Date created
2024-04-02
Creator
Stamp, Lisa K / Horsley, Carl / Te Karu, Leanne / Dalbeth, Nicola / Barclay, Murray
URL
https://hdl.handle.net/10523/23521
Related subjects
Amyloidosis - drug therapy / Colchicine - adverse effects / Drug-Related Side Effects and Adverse Reactions / Familial Mediterranean Fever - drug therapy / Gout - chemically induced / Gout - drug therapy / Gout Suppressants - adverse effects / Humans

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