Novel Chitosan-Silica Hybrid Hydrogels for Cell Encapsulation and Drug Delivery

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Title

Novel Chitosan-Silica Hybrid Hydrogels for Cell Encapsulation and Drug Delivery

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Hydrogels constructed from naturally derived polymers provide an aqueous environment that encourages cell growth, however, mechanical properties are poor and degradation can be difficult to predict. Whilst, synthetic hydrogels exhibit some improved mechanical properties, these materials lack biochemical cues for cells growing and have limited biodegradation. To produce hydrogels that support 3D cell cultures to form tissue mimics, materials must exhibit appropriate biological and mechanical p...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2021-11-12

Creator

Jayash, Soher N / Cooper, Paul R / Shelton, Richard M / Kuehne, Sarah A / Poologasundarampillai, Gowsihan

URL

https://hdl.handle.net/10523/25194

Related subjects

Anti-Bacterial Agents - chemistry / Anti-Bacterial Agents - pharmacology / Cell Culture Techniques, Three Dimensional - methods / Cell Encapsulation - methods / Cell Line, Tumor / Cell Survival - drug effects / Chitosan - chemistry / Drug Delivery Systems - methods / Enterococcus faecalis - drug effects / Humans / Hydrogels - chemistry / Hydrogels - pharmacology / Microscopy, Electron, Scanning / Phase Transition / Proton Magnetic Resonance Spectroscopy / Pseudomonas aeruginosa - drug effects / Silicon Dioxide - chemistry / Spectroscopy, Fourier Transform Infrared / Tissue Engineering - methods

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