Osteoconduction in keratin-hydroxyapatite composite bone-graft substitutes

About this item

Title

Osteoconduction in keratin-hydroxyapatite composite bone-graft substitutes

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Reconstituted keratin-hydroxyapatite (K-HA) composites have shown potential as nonload-bearing bone graft substitute material. This in vivo study investigated the bone regeneration response of keratin plus 40% HA composite materials in comparison to collagen counterparts and an unfilled defect site. The implantation site was a noncritical size defect created in the long bones (tibia) of sheep, with observations made at 1, 2, 4, 6, 8, and 12 weeks postimplantation. Porous K-HA materials displa...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2017-10-01

Creator

Dias, George Jayantha / Mahoney, Patricia / Hung, Noelyn Anne / Sharma, Lavanya Ajay / Kalita, Priyakshi / Smith, Robert Allen / Kelly, Robert James / Ali, Azam

URL

https://hdl.handle.net/10523/27741

Related subjects

Animals / Bone Regeneration - drug effects / Bone Substitutes - chemistry / Bone Substitutes - pharmacology / Durapatite - chemistry / Durapatite - pharmacology / Female / Keratins - chemistry / Keratins - pharmacology / Sheep / Tibia - injuries / Tibia - metabolism / Tibia - pathology

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