Spared motivational modulation of cognitive effort in a maternal immune activation model of schizophrenia risk

About this item

Title

Spared motivational modulation of cognitive effort in a maternal immune activation model of schizophrenia risk

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Maternal immune activation (MIA) during gestation is a significant risk factor for development of schizophrenia and other neurodevelopmental diseases. In animal models of this risk factor, MIA during pregnancy can produce offspring that recapitulate certain aspects of the behavioral and neurophysiological impairments seen in schizophrenia. Here, the authors tested the effect of polyinosinic-polycytidylic acid (poly I:C)-induced MIA in a task that explicitly assays the interaction between moti...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2018-02

Creator

Bates, Vanessa / Maharjan, Ashim / Millar, Jessica / Bilkey, David K / Ward, Ryan D

URL

https://hdl.handle.net/10523/26405

Related subjects

Animals / Attention / Cognition / Discrimination (Psychology) / Disease Models, Animal / Extinction, Psychological / Female / Male / Motivation / Poly I-C / Pregnancy / Prenatal Exposure Delayed Effects / Prepulse Inhibition / Rats, Sprague-Dawley / Reward / Schizophrenia - immunology / Schizophrenic Psychology

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