Characterization of GnRH Pulse Generator Activity in Male Mice Using GCaMP Fiber Photometry

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Title

Characterization of GnRH Pulse Generator Activity in Male Mice Using GCaMP Fiber Photometry

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Kisspeptin neurons located in the hypothalamic arcuate nucleus are thought to represent the GnRH pulse generator responsible for driving pulsatile LH secretion. The recent development of GCaMP6 fiber photometry technology has made it possible to perform long-term recordings of the population activity of the arcuate nucleus kisspeptin (ARN(KISS)) neurons in conscious-behaving mice. Using this approach, we show that ARN(KISS) neurons in intact male mice exhibit episodes of synchronized activity...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2019-03-01

Creator

Han, Su Young / Kane, Grace / Cheong, Isaiah / Herbison, Allan E.

URL

https://hdl.handle.net/10523/25815

Related subjects

Endocrinology & Metabolism / Life Sciences & Biomedicine / Science & Technology

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