Nasal high-flow therapy compared with non-invasive ventilation in COPD patients with chronic respiratory failure: A randomized controlled cross-over trial

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Title

Nasal high-flow therapy compared with non-invasive ventilation in COPD patients with chronic respiratory failure: A randomized controlled cross-over trial

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Non-invasive ventilation (NIV) is part of the standard of care for hypercapnic respiratory failure secondary to COPD, but may be poorly tolerated. Preliminary evidence suggests nasal high-flow (NHF) therapy may improve hypercapnia in COPD and be well tolerated. We compared NHF and NIV in people with COPD and chronic hypercapnic respiratory failure. Single-blind randomized controlled two-way cross-over single-centre trial was conducted in New Zealand. Twenty-four participants with stable hyper...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2019-11

Creator

McKinstry, Steven / Singer, Joseph / Baarsma, Jan Pieter / Weatherall, Mark / Beasley, Richard / Fingleton, James

URL

https://hdl.handle.net/10523/28691

Related subjects

Aged / Blood Gas Monitoring, Transcutaneous / Cannula / Carbon Dioxide - blood / Cross-Over Studies / Female / Humans / Hypercapnia - diagnosis / Hypercapnia - etiology / Hypercapnia - therapy / Male / Masks / Middle Aged / Noninvasive Ventilation - instrumentation / Noninvasive Ventilation - methods / Oxygen Inhalation Therapy - instrumentation / Oxygen Inhalation Therapy - methods / Pulmonary Disease, Chronic Obstructive - complications / Respiratory Insufficiency - blood / Respiratory Insufficiency - etiology / Respiratory Insufficiency - therapy / Single-Blind Method / Treatment Outcome

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