A MicroRNA Cluster in the DLK1-DIO3 Imprinted Region on Chromosome 14q32.2 Is Dysregulated in Metastatic Hepatoblastomas

About this item

Title

A MicroRNA Cluster in the DLK1-DIO3 Imprinted Region on Chromosome 14q32.2 Is Dysregulated in Metastatic Hepatoblastomas

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Hepatoblastoma (HB) is the most common malignant liver neoplasm in children. Despite progress in HB therapy, outcomes for patients with metastatic disease remain poor. Dysregulation of miRNA expression is one of the potential epigenetic mechanisms associated with pathogenesis of HB. However, miRNA profiles related to the different stages of HB tissues and cells, in particular of lung metastatic tumor cells, are unknown. In the present study, using array-based miRNA expression and DNA methylat...

Read more

Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2020-11-12

Creator

Honda, Shohei / Chatterjee, Aniruddha / Leichter, Anna L. / Miyagi, Hisayuki / Minato, Masashi / Fujiyoshi, Sunao / Ara, Momoko / Kitagawa, Norihiko / Tanaka, Mio / Tanaka, Yukichi / Shinkai, Masato / Hatanaka, Kanako C. / Taketomi, Akinobu / Eccles, Michael R.

URL

https://hdl.handle.net/10523/28537

Related subjects

Oncology

What is the copyright status of this item?

Share, Modify, Use commercially

See below for specifics about how you may use this item.

More Information

University of Otago has this to say about the rights status of this item:

CC BY V4.0

What can I do with this item?

You must always check with University of Otago to confirm the specific terms of use, but this is our understanding:

Non-infringing use

NZ Copyright law does not prevent every use of a copyright work. You should consider what you can and cannot do with a copyright work.

Share it

This item is suitable for copying and sharing with others, without further permission.

Modify it

This item is suitable for modifying, remixing and building upon, without further permission.

Use it commercially

This item is suitable for commercial use, without further permission.