Randomized controlled trial of oxygen saturation targets in very preterm infants: two year outcomes

About this item

Title

Randomized controlled trial of oxygen saturation targets in very preterm infants: two year outcomes

Content partner

University of Otago

Collection

Otago University Research Archive

Description

To assess whether an oxygen saturation (Spo2) target of 85%-89% compared with 91%-95% reduced the incidence of the composite outcome of death or major disability at 2 years of age in infants born at <28 weeks' gestation. A total 340 infants were randomized to a lower or higher target from <24 hours of age until 36 weeks' gestational age. Blinding was achieved by targeting a displayed Spo2 of 88%-92% using a saturation monitor offset by ±3% within the range 85%-95%. True saturations were displ...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2014-07-01

Creator

Darlow, Brian A / Marschner, Simone L / Donoghoe, Mark / Battin, Malcolm R / Broadbent, Roland S / Elder, Mark J / Hewson, Michael P / Meyer, Michael P / Ghadge, Alpana / Graham, Patricia / McNeill, Nicolette J / Kuschel, Carl A / Tarnow-Mordi, William O / Benefits Of Oxygen Saturation Targeting-New Zealand (BOOST-NZ) Collaborative Group

URL

https://hdl.handle.net/10523/31894

Related subjects

Australia / Child, Preschool / Disability Evaluation / Double-Blind Method / Female / Gestational Age / Humans / Infant / Infant, Newborn / Infant, Premature / Infant, Premature, Diseases - metabolism / Infant, Premature, Diseases - mortality / Infant, Premature, Diseases - therapy / Infant, Very Low Birth Weight - metabolism / Male / Outcome Assessment (Health Care) / Oxygen - blood / Oxygen Inhalation Therapy - methods / Risk Assessment

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