Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease

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Title

Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease

Content partner

University of Otago

Collection

Otago University Research Archive

Description

The New Zealand sea lion (NZSL, Phocarctos hookeri) is a Threatened marine mammal with a restricted distribution and a small, declining, population size. The species is susceptible to bacterial pathogens, having suffered three mass mortality events since 1998. Understanding the genetic factors linked to this susceptibility is important in mitigating population decline. The gene solute carrier family 11 member a1 (Slc11a1) plays an important role in mammalian resistance or susceptibility to a ...

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Format

Research paper

Research format

Scholarly text / Journal article

Thesis level

Article

Date created

2015-04-14

Creator

Osborne, Amy J / Pearson, John / Chilvers, B Louise / Kennedy, Martin A / Gemmell, Neil J

URL

https://hdl.handle.net/10523/30063

Related subjects

Animals / Bacterial Infections - epidemiology / Bacterial Infections - genetics / Bacterial Infections - veterinary / Base Sequence / Binding Sites / Cation Transport Proteins - genetics / Cation Transport Proteins - physiology / Disease Outbreaks - veterinary / Disease Resistance - genetics / Dogs - genetics / Endangered Species / Gene Frequency / Genetic Association Studies / Genetic Predisposition to Disease / Haplotypes - genetics / Immunity, Innate - genetics / Introns - genetics / Mammals - classification / Mammals - genetics / Microsatellite Repeats / Molecular Sequence Data / Phylogeny / Polymorphism, Genetic / Promoter Regions, Genetic - genetics / Sea Lions - classification / Sea Lions - genetics / Sea Lions - immunology / Sequence Alignment / Sequence Homology, Nucleic Acid / Species Specificity / Transcription Factors - metabolism

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