Type II Toxin-Antitoxins: Structural and Functional Aspects of Type II Loci in Mycobacteria

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Title

Type II Toxin-Antitoxins: Structural and Functional Aspects of Type II Loci in Mycobacteria

Content partner

University of Otago

Collection

Otago University Research Archive

Description

Several prokaryotes have genomes that are densely populated with toxin–antitoxin (TA) loci. For example, the aquatic bloom-forming cyanobacterium Microcystis aeruginosa habours more than 110 TA loci, and the nematode symbiont Photorhabdus luminescens has at least 58 TAs encoded in its genome. Amongst this group of unrelated bacteria lies Mycobacterium tuberculosis whose genome encodes more than 68 TAs. M. tuberculosis causes the devastating human disease tuberculosis (TB) and is, therefore, t...

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Format

Research paper

Research format

Scholarly text / Book item

Thesis level

Book Section

Date created

2012-10-19

Creator

Arcus, Vickery L. / Cook, Gregory M.

URL

https://hdl.handle.net/10523/39244

Related subjects

Antitoxin Gene / Genome Decay / Mycobacterium Vanbaalenii / RelE Toxin / Target mRNA Transcript

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