Research paper
Blocking natural antibodies with Kode technology to investigate false positives in an immunoassay
About this item
- Title
- Blocking natural antibodies with Kode technology to investigate false positives in an immunoassay
- Content partner
- University of Otago
- Collection
- Otago University Research Archive
- Description
Objectives: Immunoassays suffer from false positives due to interference from non-specific antibodies, regardless of the target antigen or antibody under test. This research investigated the possibility that two human antibodies; anti-Gal and anti-Forsmann (Fs), were a cause of false positives in a syphilis immunoassay. A further aim was to establish the minimum concentration of synthetic antigens able to block activity of anti-Gal and anti-Fs in human plasma samples. Methods: Twenty plasma d...
- Format
- Research paper
- Research format
- Scholarly text / Journal article
- Thesis level
- Article
- Date created
- 2024-07-01
- Creator
- Perry, Holly E / Mak, Selene S
- URL
- https://hdl.handle.net/10523/41978
- Related subjects
- Antibodies / Antigen-antibody reactions / Antigens / Blood donors / Investigations / Polyacrylamide / Syphilis / Viral antibodies
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Copyright © The Author(s) 2024. This work was first published in New Zealand Journal of Medical Laboratory Science (New Zealand Institute of Medical Laboratory Science). This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://www.creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, provided that the original work is properly attributed to the creator(s) and the source, a link to the Creative Commons license is provided, and any changes made are indicated.
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