Systems biology of synaptic plasticity: a review on N-methyl-D-aspartate receptor mediated biochemical pathways and related mathematical models

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Title

Systems biology of synaptic plasticity: a review on N-methyl-D-aspartate receptor mediated biochemical pathways and related mathematical models

Content partner

Lincoln University

Collection

Lincoln University Research Archive

Description

Synaptic plasticity, an emergent property of synaptic networks, has shown strong correlation to one of the essential functions of the brain, memory formation. Through understanding synaptic plasticity, we hope to discover the modulators and mechanisms that trigger memory formation. In this paper, we first review the well understood modulators and mechanisms underlying N-methyl-D-aspartate receptor dependent synaptic plasticity, a major form of synaptic plasticity in hippocampus, and then comm...

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Format

Research Paper

Research format

Journal article

Date created

2014-08

Creator

He, Y / Kulasiri, Don / Samarasinghe, Sandhya

URL

https://hdl.handle.net/10182/8350

Related subjects

synaptic plasticity / systems biology / memory formation / LTP / LTD / Brain / Humans / Calcium / Calmodulin / Receptors, Glutamate / Receptors, N-Methyl-D-Aspartate / Memory / Systems Biology / Signal Transduction / Neuronal Plasticity / Models, Biological / Biochemistry and Cell Biology / Medical Biochemistry and Metabolomics not elsewhere classified / Biological sciences / Engineering

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