In vitro proteolysis of ovine lens crystallins by calpain II : A dissertation submitted in partial fulfilment of the requirements for the Degree of Bachelor of Science with Honours

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Title

In vitro proteolysis of ovine lens crystallins by calpain II : A dissertation submitted in partial fulfilment of the requirements for the Degree of Bachelor of Science with Honours

Content partner

Lincoln University

Collection

Lincoln University Research Archive

Description

A cataract is any opacity of the lens caused by unregulated protein aggregation. Cataracts are the major cause of human blindness worldwide and it is thought that calpain-induced degradation of the major lens proteins, the crystallins, is an important component in many types of cataract.. At Lincoln University, a heritable cataract in sheep is being studied. The aim of this project was to set up an in vitro system to investigate the ovine crystallin degradation products produced by calpain II...

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Format

Research Paper

Research format

Thesis

Thesis level

Other

Date created

2003

Creator

Hancock, A. J.

URL

https://hdl.handle.net/10182/15802

Related subjects

calpain II / proteolysis / crystallins / lens / ovine / incubation / cataract / degradation / cleavage / chromatography / SDS PAGE / Analytical biochemistry / Animal cell and molecular biology

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