Modulation of long-term potentiation following microdoses of LSD captured by thalamo-cortical modelling in a randomised, controlled trial

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Title

Modulation of long-term potentiation following microdoses of LSD captured by thalamo-cortical modelling in a randomised, controlled trial

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The University of Auckland Library

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ResearchSpace@Auckland

Description

BackgroundMicrodosing psychedelics is a phenomenon with claimed cognitive benefits that are relatively untested clinically. Pre-clinically, psychedelics have demonstrated enhancing effects on neuroplasticity, which cannot be measured directly in humans, but may be indexed by non-invasive electroencephalography (EEG) paradigms. This study used a visual long-term potentiation (LTP) EEG paradigm to test the effects of microdosed lysergic acid diethylamide (LSD) on neural plasticity, both acutely...

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Research paper

Research format

Journal article

Creator

Murphy, Robin J / Godfrey, Kate / Shaw, Alexander D / Muthukumaraswamy, Suresh / Sumner, Rachael L

URL

https://hdl.handle.net/2292/70227

Related subjects

Humans / Lysergic Acid Diethylamide / Hallucinogens / Electroencephalography / Neuronal Plasticity / Long-Term Potentiation / Adult / Male / Dynamic causal modelling / Neuroplasticity / Psychedelics / 5202 Biological Psychology / 32 Biomedical and Clinical Sciences / 52 Psychology / Clinical Trials and Supportive Activities / Clinical Research / Eye Disease and Disorders of Vision / Neurosciences / 6.1 Pharmaceuticals / Neurological / Science & Technology / Life Sciences & Biomedicine / Neurosciences & Neurology / STIMULATION / PLASTICITY / INDUCTION / NEURONS / CORTEX / AREA / LTP / 0601 Biochemistry and Cell Biology / 1109 Neurosciences / 1702 Cognitive Sciences / 3209 Neurosciences

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