LSDDEP2: study protocol for a randomised, double-dummy, triple-blind, active placebo-controlled, parallel groups trial of LSD microdosing in patients with major depressive disorder.

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Title

LSDDEP2: study protocol for a randomised, double-dummy, triple-blind, active placebo-controlled, parallel groups trial of LSD microdosing in patients with major depressive disorder.

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The University of Auckland Library

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ResearchSpace@Auckland

Description

BACKGROUND: Major depressive disorder (MDD) poses a significant global health burden with available treatments limited by inconsistent efficacy and notable side effects. Classic psychedelics, including lysergic acid diethylamide (LSD), have garnered attention for their potential in treating psychiatric disorders. Microdosing, the repeated consumption of sub-hallucinogenic doses of psychedelics, has emerged as a self-treatment approach for depression within lay communities. Building upon preli...

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Format

Research paper

Research format

Journal article

Creator

Daldegan-Bueno, Dimitri / Donegan, Carina Joy / Forsyth, Anna / Sumner, Rachael Louise / Murphy, Robin J / Menkes, David B / Evans, William / Hoeh, Nicholas / Sundram, Frederick / Reynolds, Lisa M / Ponton, Rhys / Cavadino, Alana / Smith, Todd / Roop, Partha / Allen, Nathan / Abeysinghe, Binu / Svirskis, Darren / Bansal, Mahima / Muthukumaraswamy, Suresh

URL

https://hdl.handle.net/2292/70242

Related subjects

LSD / Major depressive disorder / Microdosing / Psychedelics / Randomised controlled trial / Humans / Depressive Disorder, Major / Lysergic Acid Diethylamide / Hallucinogens / Double-Blind Method / Randomized Controlled Trials as Topic / Treatment Outcome / Adult / Clinical Trials, Phase II as Topic / Male / Female / Middle Aged / Young Adult / Time Factors / 1102 Cardiorespiratory Medicine and Haematology / 1103 Clinical Sciences / 3202 Clinical sciences / 4202 Epidemiology / 4203 Health services and systems

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