Porcine colonoids and enteroids keep the memory of their origin during regeneration

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Title

Porcine colonoids and enteroids keep the memory of their origin during regeneration

Content partner

Massey University

Collection

Massey Research Online

Description

The development of alternative in vitro culture methods has increased in the last decade as three-dimensional organoids of various tissues, including those of the small and large intestines. Due to their multicellular composition, organoids offer advantages over traditionally used immortalized or primary cell lines. However, organoids must be accurate models of their tissues of origin. This study compared gene expression profiles with respect to markers of specific cell types (stem cells, ent...

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Format

Research paper

Research format

Journal article

Date created

2021-05-01

Creator

Barnett AM / Mullaney JA / Hendriks C / Le Borgne L / McNabb WC / Roy NC

URL

https://hdl.handle.net/10179/71762

Related subjects

barrier maturation / colon / differentiation / intestinal epithelium / stem cells / Animals / Biomarkers / Cell Differentiation / Cell Lineage / Cell Proliferation / Colon / Gene Expression Regulation / Ileum / Intestinal Mucosa / Male / Organoids / Phenotype / Signal Transduction / Sus scrofa / Time Factors / Tissue Culture Techniques / Transcriptome

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(c) 2021 The Author/s

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