Research paper
The Role of Gut-Brain Tryptophan Metabolism and Fatty Acid Peroxidation in the Effect of Sleep Deprivation on Anxiety and Depression in PCOS Mice
About this item
- Title
- The Role of Gut-Brain Tryptophan Metabolism and Fatty Acid Peroxidation in the Effect of Sleep Deprivation on Anxiety and Depression in PCOS Mice
- Content partner
- University of Otago
- Collection
- Otago University Research Archive
- Description
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of childbearing age. Numerous studies have indicated a significantly elevated incidence of depression and anxiety in women affected by PCOS, often attributed to dysbiosis of gut microbiota resulting from poor sleep quality. However, the intricate relationship between sleep disorders, gut microbiota, and depression/anxiety in PCOS remains unclear. In this study, we aimed to elucidate the effects of sleep depriva...
- Format
- Research paper
- Research format
- Scholarly text / Journal article
- Thesis level
- Article
- Date created
- 2025-05-31
- Creator
- Han, Ting / Liu, Shangjing / Liu, Hao / Wang, Xin / Yang, Xiaojia / Chan, ShanAn / Tumanov, Sergey / Cannon, Richard D / Yang, Yang / Han, Ting-Li
- URL
- https://hdl.handle.net/10523/46468
- Related subjects
- PCOS / Gut-brain axis / Tryptophan / Depression / Anxiety / Lipid metabolism / Sleep deprivation
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Copyright © Springer Nature 2025. All rights reserved. This work was first published in Molecular Neurobiology (Springer Nature). The open access link to the subscription article is provided under the Springer Nature SharedIt Content-Sharing Initiative (https://www.springernature.com/gp/researchers/sharedit) making the view-only full-text article freely and legally accessible to anyone for research purposes and private study via the link: https://rdcu.be/eqdDG.
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Report this itemDigitalNZ brings together more than 30 million items from institutions so that they are easy to find and use. This information is the best information we could find on this item. This item was added on 10 June 2025, and updated 14 June 2025.
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